Sunday, 31 March 2013

UPS to forfeit $40 million over illegal online pharmacy shipments

(Reuters) - United Parcel Service Inc has agreed to forfeit $40 million it earned from illegal Internet pharmacies shipping drugs using its services, U.S. authorities said Friday.

As part of the settlement, UPS entered a non-prosecution agreement with the U.S. Department of Justice.

The company also agreed to put a compliance program into place to prevent illegal online pharmacies from distributing drugs through its shipping services in the future, authorities said.

"Good corporate citizens like UPS play an important role in halting the flow of illegal drugs that degrade our nation's communities," Northern California U.S. Attorney Melinda Haag said in a statement.

UPS cooperated with the investigation, prosecutors said.

Prosecutors said UPS was on notice from 2003 to 2010 that Internet pharmacies were shipping drugs without prescriptions, yet the company didn't put procedures in place to shut down their accounts.

"We believe we have an obligation and responsibility to help curb the sale and shipment of drugs sold through illegal Internet pharmacies," said Susan Rosenberg, a UPS spokeswoman.

(Reporting by Nate Raymond in New York; Editing by Chizu Nomiyama)

Source: http://news.yahoo.com/ups-forfeit-40-million-over-illegal-online-pharmacy-183147419--sector.html

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Saturday, 30 March 2013

3 of 4 reptiles stolen from Calif. museum found

(AP) ? A Central California science museum has recovered three of four reptiles stolen in a burglary caught on surveillance video, and arrested a suspect in the heist.

The Discovery Center's education coordinator Ian Goudelock says a 3 1/2-foot savannah monitor lizard, red-tailed boa constrictor and a ball python are back at the Fresno museum on Friday. A 3-foot-long ball python remains missing.

The suspect broke into the museum on Wednesday night or Thursday morning, smashed the tanks that held the four reptiles and made off with them in a garbage bag. The suspect also went into the center's gift shop and stole children's toys, the phone system and the security monitor.

Fresno police says they made an arrest on suspicion of the burglary, but the suspect's name was not immediately available.

___

Information from: The Fresno Bee, http://www.fresnobee.com

Source: http://hosted2.ap.org/APDEFAULT/aa9398e6757a46fa93ed5dea7bd3729e/Article_2013-03-29-Reptiles%20Stolen/id-5f8bf82f45064db8a442040dcedff2d9

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Hillsborough County sports briefs - Golf Blog

Junior Women?s tournament: The Plant City Junior Women?s Club holds its inaugural charity golf tournament April 6 at Walden Lake Golf and Country Club, 2001 Clubhouse Drive.

This event will be held to raise funds for the club?s Plant City Shoe Project. There will be trophies, prizes and a 50-50 drawing. For information contact Stephanie Eisenbach, president and Shoe Project chairwoman at (813) 468-0230 or Steph57b@yahoo.com.

Brandon Ballet golf tournament: Brandon Ballet holds a four-person golf scramble April 28 at River Hills Golf and Country Club, 3943 New River Hills Parkway.

Registration will begin at 11:30 a.m. with a shotgun start at 1 p.m. Prizes will be provided for first, second and third as well as longest drive and closest to the pin. A post-tournament dinner will be served.

Sponsorships remain available and all proceeds go to Brandon Ballet.

The cost is $85 per individual or $320 per group if you register before April 19. For information, contact Monica Frost at (813) 545-6688.

Sickle Cell Classic: The Sickle Cell Association of Hillsborough County will host an Old School Celebrity Golf Classic April 20 at Heritage Isles Golf and Country Club, 10630 Plantation Bay Drive.

The four-person scramble begins with registration at 7 a.m., a shotgun start at 8 a.m. and an awards luncheon at 12:30 p.m. Pairings will be provided for individual golfers. Awards will be presented for first, second and third along with closest to the pin and longest drive. The cost is $85 per golfer.

Former NFL and USFL defensive back Luther Bradley will host the tournament, and sponsorship opportunities remain available. For information, go to oldschoolcelebritygc.com.

Holy Innocents tourney: Holy Innocents Espicopal Church will hold a golf tournament May 18 at Bloomingdale Golfers Club, 4113 Great Golfer?s Place. The best ball scramble is $240 for foursomes and $65 for individuals. Price includes: cart, range balls, gift bag, prizes and a meal. Interested players and sponsors can contact Steve Purifoy at spurifoy@earthlink.net or (813) 495-4307.

From www.tampabay.com

Source: http://golf.blogm4u.com/2013/03/30/hillsborough-county-sports-briefs/

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Corporate Limo Party Is A Classy Service To Make An Impact

By: Ronald Arny Corporate Limo Party Is A Classy Service To Make An Impact

Drive in a limousine is immersion in the world of leisure. For corporate limo party there are models of upscale road transport that accommodate different numbers of people. The reason could be any to hire this service but the end is one and it is the comfort of the riders and their exposure to ultimate luxury. It is very common now to have such corporate events in order to celebrate success of a company or an organization. Sense of participation is given to the employees and they become more responsible in their work towards the company. The ride to the venue is very short but it has a significant importance and makes the day.

The best possible transport of the road is available now in state of US. It is a luxurious service that is for the executive class. During the ride they enjoy the features of the vehicles and the expertise of the chauffeurs. Sometimes they are entertained with the complimentary drink on the way to the destination. The riders enjoy the skills of the drivers and the luxury of the cars. They get to the venue of party or meeting in a style and in a fresh mood. Stretched limo and normal limo are present their in the catalogue of the limo service providers. The customers have the liberty to select the car of their choice for the purpose of transportation. The service is used for many other objectives and the customers feel pride to hire it.

The service is a blessing to enjoy the high class that a vehicle could offer in the road transport. The variety of the vehicles and their maintenance is compulsory to attract the customers. In addition to the availability of the resources the dealing of the booking staff and that of the chauffeurs with the guests also play a vital role. The mode of the party sets the theme of the ride and the service providers strictly follow it. For a meeting or a conference a corporate limo service is rather sophisticated and serious in outlook as compare tot that of the celebration of the success.

The interior and exterior of the vehicles are very well maintained to give one hundred percent to the clients and never let them down with the service quality. The drivers are also well aware of the needs of the customers so they act accordingly. The vehicles in the lot have different per hour charges and that are mentioned on the websites of the service providers. The customers can ask for the charges of a particular limo on a specific day and time on the website as well as on the phone.


About the Author:
Ronald Arny is the Junior marketing executive at Washington DC Limo Services. You can find more information or ask him any question about Corporate Limo Party or Washington DC Limo Services

Article Originally Published On: http://www.articlesnatch.com


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  • Ideas That Help Make Traveling Less Of A Burden By: Dewayne Gates | Mar 29th 2013 - This article will give you advice on how to have a pleasant trip, whether you are traveling to visit relatives, or to go on a cruise. Traveling by trains, boats, cars or planes all share some of the same basic tips.
  • Tags: coach hire london, coach travel london, coach hire edinburgh, coach hire prices, coach hire quotes...
  • Tips For Successfully Planning And Making That Trip By: Dewayne Gates | Mar 29th 2013 - An excellent method of exploring new areas and gaining some new insight into the world around us is traveling. Traveling can be very costly and take up a lot of time though. Read on for some advice on how to have the best vacation you can that's within your time limit and budget.
  • Tags: corporate coach hire, coach travel for companies, executive coach hire, vip coach hire london, company coach hire...
  • Acquiring Airport Transfers And Other Tricks For Hassle-free Holiday Getaway By: Rob | Mar 29th 2013 - It's also smart to book your seat when you get your ticket instead of selecting a seat while you're at the check in counter. So a number of other individuals will be flying that you could get stuck with bad seats or at least, discover that you and your loved ones are dispersed all ...
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  • Perfecting Nihongo While Earning A Living In The Land Of The Rising Sun By: Penny Monroe | Mar 29th 2013 - Studying Japanese is the perfect strategy to learn the language of the people from the Land of the Rising Sun.
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  • Thiruvananthapuram- Evergreen City Of India By: Gabrieljohn | Mar 29th 2013 - Thiruvananthapuram also called as Trivandrum. The name Trivandrum was re-christened by English. It is the capital city of Kerala. It lies in the west coast of India.
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  • Shoghi ""on The Mountains Near Shimla By: Gabrieljohn | Mar 29th 2013 - Shoghi is a small town near Shimla situated in the state of Himachal Pradesh. Shoghi is at about 13 kilometers beforereaching Shimla on the Ambala Shimla National Highway.
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  • Pune "" The City Of Virtue By: Gabrieljohn | Mar 29th 2013 - Famous for the educational institutions and vibrant nightlife, Pune is the second biggest city in the Indian state of Maharashtra. The city welcomes thousands of students from all over India every year.
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Asia stocks modestly higher after S&P hits record

BANGKOK (AP) ? Asian stock markets were mostly higher Friday as momentum carried over from yet another record high on Wall Street.

The Standard and Poor's 500 index closed at its highest level ever Thursday, driven by more encouraging data on the U.S. economic recovery. The government said the economy grew at an annual rate of 0.4 percent in the October-December quarter, slightly better than previous estimates. The revision reflected stronger business investment and export sales.

South Korea's Kospi rose 0.8 percent to 2,010.40. Taiwan's TAIEX advanced 0.7 percent to 7,920.38. Markets in Hong Kong, India, Australia, New Zealand, Indonesia, Philippines and Singapore were shut for Good Friday.

Japan's Nikkei reversed early losses to rise 0.4 percent at 12,389.16. Gains were muted, however, as the yen leveled off against the dollar and the government released figures for February showing the country's jobless rate edging up while industrial production fell slightly.

Newly appointed central bank governor, Haruhiko Kuroda, has pledged to work with the government to end decades of growth-inhibiting deflation. His outspoken calls for action have raised hopes for results but some analysts said they may also have created unrealistic expectations for a turnaround.

"Unfortunately, the markets' expectations of the new Governor are so high that they will be almost impossible to meet, let alone beat," said analysts at Capital Economics in a market commentary.

Shares in mainland China fell amid limited trading volume, analysts said. The Shanghai Composite Index was 0.1 percent lower at 2,233.23 and the Shenzhen Composite Index fell 0.3 percent to 927.06.

Peng Yunliang, a Shanghai-based analyst, said shares in brokerage houses declined following the release Thursday of official policies aimed at tightening control over wealth management products.

In Europe on Thursday, markets responded positively to the calm reopening of Cyprus's banks. Banks in the Mediterranean island nation were shut for nearly two weeks as the government negotiated a rescue loan from international lenders to prevent the financial system from collapsing. The FTSE 100 index of leading British shares, Germany's DAX and France's CAC-40 all closed higher Thursday.

Italy's political uncertainty will also remain in the spotlight. Following inconclusive elections around a month ago, the country is still without a government, and that's raised concerns over its future economic path. Italy is the third-largest economy of the 17 countries that use the euro.

The Standard and Poor's 500 index closed at a record Thursday, surpassing its previous record close of 1,565.15 set in October 2007. The Dow, which surpassed its previous all-time high at the start of the month, also rose.

The Dow Jones industrial average gained 0.4 percent to close at 14,578.54. The S&P 500 advanced 0.4 percent to close at 1,569.19. The Nasdaq composite index added 0.3 percent to 3,267.52. U.S. stock markets will be shut for the Good Friday holiday. Thursday was the last trading day of the first quarter.

The New York Mercantile Exchange, where benchmark oil is traded, was closed for the Good Friday holiday.

In currencies, the euro rose to $1.2826 from $1.2822 late Thursday in New York. The dollar fell to 94.07 yen from 94.13 yen.

___

AP researcher Fu Ting contributed from Shanghai.

Source: http://news.yahoo.com/asia-stocks-modestly-higher-p-hits-record-052945487--finance.html

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Friday, 29 March 2013

Hands-on with Katamari Damacy creator's crazy 16-button game controller (video)

DNP Special 16button controller gets demoed with Katamari Damacy's creator's new game

You don't often see a video game specifically designed for a 16-button bespoke controller and for a special one-time party, but that's exactly what Keita Takahashi has done with Tenya Wanya Teens. If that name sounds familiar, it's because Takahashi is responsible for the enormously popular game franchise that is Katamari Damacy along with cult favorite Noby Noby Boy. Teens is his first foray as an independent creator under Uvula, a studio he formed with his wife Asuka Sakai, and is a result of a collaboration with event organizers Wild Rumpus and video game website Venus Patrol. As for the party in question, it's one that is being held concurrently with the 2013 Game Developers Conference in San Francisco, which is where we saw the controllers and the game in action.

As you can see above, the controller looks a lot like a modified arcade stick. A hand-made effort by programmer George Buckenham, both boxes were built in about five days for around 200£ ($302.50) each. According to Buckenham, the easiest part was assembling the electronics; it was the plywood housing that took him awhile to master. As for the game, Tenya Wanya Teens is a highly whimsical effort that is described as "a coming-of-age tale about love, hygiene, monsters and finding discarded erotic magazines in the woods." Tasks include peeing in the shower, punching monsters and taking on grizzly bears.

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Source: http://www.engadget.com/2013/03/27/tenya-wanya-teens-16-button-controller/

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MN Supreme Court: Foster parents can adopt children even if ...

Posted at 12:10 PM on March 27, 2013 by Bob Collins (2 Comments)
Filed under: Crime and Justice

A sharply divided Minnesota Supreme Court today ruled that two young African American girls, born to apparent drug addicts, can be adopted by their white foster parents rather than their grandparents, despite a state law that appears to favor adoption by family members over others.

The decision appeared to hinge on one word in the law: consider.

The two girls both tested positive for cocaine upon birth and have had developmental problems since. They were removed from the home almost immediately by Hennepin County and put in the care of foster parents.

Later, the foster parents agreed to adopt the girls after the grandparents initially expressed interest in the adoption, but didn't cooperate with an in-home placement study in Mississippi. After some delay, they relented, the study was turned in, and the two competing adoption petitions went before a district court, which ruled adoption by the foster parents was in the best interest of the girls. The court said given their special needs, there could be damage by removing the girls from the only home they ever knew.

But the grandparents appealed, saying state law favors relatives over "an important friend with whom the child has resided or had significant compact." They said the district court should have ruled they were fit to adopt, and the process should have stopped there.

But in her opinion today, Justice Lori Gildea disagreed, saying the law only requires courts to consider the adoption petition of a relative first and then the foster parents. But it does not prefer a relative over a non-relative.

"It is true that the district court did not analyze the grandparents' petition in its entirety before turning to analyze the foster parents' petition," Justice Gildea wrote. "The court also did not expressly conclude in its order that it was not in the girls' best interests to be adopted by their grandparents, which would be the better practice. But the court did consider and then form a conclusion about the grandparents' petition with respect to each factor before considering the foster parents' petition on that factor."

But the grandparents are African American while the foster parents are white and the issue of tending to the "cultural needs" of adoptive children has been controversial in Minnesota and elsewhere, even though state law requires cultural needs be considered.

"The foster parents have adopted two sons who are Asian-American and African-American respectively, and an African-American friend lives with the family," Justice Gildea said in rejecting the argument. "The district court did not specifically explain how the foster parents were able to meet the cultural needs of the children other than to find that the foster parents 'believe that diversity is very important.' We share the court of appeals' concern that the district court's findings on this factor 'grossly simplify' the girls' needs... But given our deferential standard of review, we cannot say that the court's analysis of this factor renders its overall best-interests analysis an abuse of discretion."

But in his dissent, Justice Alan Page, joined by Justice David Stras, said Gildea's interpretaton of the law would require courts to consider a relative's adoption petition and a non-relative's "side by side and at the same time," and effectively makes the state statute "meaningless."

"If the Legislature had intended for us to read the statute the way the concurrence suggests, there would have been no reason to require courts to consider placement in a particular order, and absolutely no reason to distinguish between relatives and others," Justice Page wrote.

And that's important in a case like this, Page noted, because the Legislature's authors wrote the statute with race differences in mind. "The authors of the amendments were no doubt concerned that eliminating race as a consideration in adoptive and foster care placements might have the unintended effect of decreasing the likelihood that children from racial minorities would be adopted by relatives," he wrote. "One way to mitigate these potential negative effects was to strengthen the statutory emphasis on placement with relatives by requiring that placement with relatives be considered before placement with others."

Justice Wilhelmina Wright agreed with Justice Page that the district court should've considered the grandparents' petition first before moving on to the foster parents' adoption petition, but she said "the best interests of the children could not have been ascertained without consideration of the impact of the proposed move on these young children."

Here's today's full decision.


Comments (2)

So, the white majority of the MN Supreme Court overwhelmingly determined it "in the best interest" of two black kids to be placed with white foster parents, while the black minority of the Court unanimously agreed that the black kids should be placed with their black grandparents.

That about sums it up? Anybody else see anything desperately wrong with this whole picture? Bob?


Will the grandsparents have a visitation right? What do the adoptive parents say about this? I don't think about the case in the framework of race, but of larger family: even if your parents fail you, the larger family should be a place where failings are buffered and a sense of belonging established. Recent studies show that those kids deal best with adversities who have heard their larger family's story, of adversities and persistence. The court takes that away from those children. The law seems to say that the larger family is relevant, the Supreme Court that it is not - a case of legislation from the bench?


Source: http://minnesota.publicradio.org/collections/special/columns/news_cut/archive/2013/03/mn_supreme_court_foster_parent.shtml

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Tuesday, 26 March 2013

Kerry stikes out in Baghdad (Powerlineblog)

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New mechanism for long-term memory formation discovered

Mar. 25, 2013 ? UC Irvine neurobiologists have found a novel molecular mechanism that helps trigger the formation of long-term memory. The researchers believe the discovery of this mechanism adds another piece to the puzzle in the ongoing effort to uncover the mysteries of memory and, potentially, certain intellectual disabilities.

In a study led by Marcelo Wood of UC Irvine's Center for the Neurobiology of Learning & Memory, the team investigated the role of this mechanism -- a gene designated Baf53b -- in long-term memory formation. Baf53b is one of several proteins making up a molecular complex called nBAF.

Mutations in the proteins of the nBAF complex have been linked to several intellectual disorders, including Coffin-Siris syndrome, Nicolaides-Baraitser syndrome and sporadic autism. One of the key questions the researchers addressed is how mutations in components of the nBAF complex lead to cognitive impairments.

In their study, Wood and his colleagues used mice bred with mutations in Baf53b. While this genetic modification did not affect the mice's ability to learn, it did notably inhibit long-term memories from forming and severely impaired synaptic function.

"These findings present a whole new way to look at how long-term memories form," said Wood, associate professor of neurobiology & behavior. "They also provide a mechanism by which mutations in the proteins of the nBAF complex may underlie the development of intellectual disability disorders characterized by significant cognitive impairments."

How does this mechanism regulate gene expression required for long-term memory formation? Most genes are tightly packaged by a chromatin structure -- chromatin being what compacts DNA so that it fits inside the nucleus of a cell. That compaction mechanism represses gene expression. Baf53b, and the nBAF complex, physically open the chromatin structure so specific genes required for long-term memory formation are turned on. The mutated forms of Baf53b did not allow for this necessary gene expression.

"The results from this study reveal a powerful new mechanism that increases our understanding of how genes are regulated for memory formation," Wood said. "Our next step is to identify the key genes the nBAF complex regulates. With that information, we can begin to understand what can go wrong in intellectual disability disorders, which paves a path toward possible therapeutics."

Findings appear online today in Nature Neuroscience.

Annie Vogel-Ciernia, Dina Matheos, Eniko Kramar, Soraya Azzawi, Yuncai Chen, Christophe Magnan, Michael Zeller, Angelina Sylvain, Jakob Haettig, Yousheng Jia, Anthony Tran, Richard Dang, Rebecca Post, Meredith Chabrier, Alex Babayan, Pierre Baldi, Dr. Tallie Z. Baram and Gary Lynch of UC Irvine; Ruth Barrett of Oregon Health & Science University; and Jiang Wu and Gerald Crabtree of Stanford University contributed to the study.

Grants from the National Institutes of Health (MH081004, DA025922, T32-AG00096-29, P01 NS045260, NS 28912, LM010235 and MH73136), the Office of Naval Research (N00014-10-1-0072), the National Science Foundation (IIS-0513376) and the National Library of Medicine (T15 LM07443) supported the research.

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The above story is reprinted from materials provided by University of California - Irvine.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Annie Vogel-Ciernia, Dina P Matheos, Ruth M Barrett, Enik? A Kram?r, Soraya Azzawi, Yuncai Chen, Christophe N Magnan, Michael Zeller, Angelina Sylvain, Jakob Haettig, Yousheng Jia, Anthony Tran, Richard Dang, Rebecca J Post, Meredith Chabrier, Alex H Babayan, Jiang I Wu, Gerald R Crabtree, Pierre Baldi, Tallie Z Baram, Gary Lynch, Marcelo A Wood. The neuron-specific chromatin regulatory subunit BAF53b is necessary for synaptic plasticity and memory. Nature Neuroscience, 2013; DOI: 10.1038/nn.3359

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/_cG8hngy3l8/130325135357.htm

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Central African Republic suspended from African Union, says official

ADDIS ABABA (Reuters) - The African Union has suspended the Central African Republic after rebels seized power in the country and has imposed travel bans and asset freezes on insurgent leaders, a senior AU official said on Monday.

The power grab by the Seleka rebel coalition, the latest in a series of coups and rebellions since the mineral-rich nation won independence from France in 1960, has already been condemned by the African Union and United Nations.

"The (Peace and Security) Council has decided to suspend with immediate effect the Central African Republic from all the African Union's activities," the AU's Commissioner for Peace and Security, Ramtane Lamamra, told reporters in Addis Ababa, where the African organization is based.

The United States, France and regional powerbroker Chad have called on Seleka leader Michel Djotodia to respect a January power-sharing deal signed in the Gabonese capital Libreville. A rebel leader has pledged to name a power-sharing government.

The Libreville agreement had created a government drawn from rebel leaders, the civilian opposition and loyalists of former president Francois Bozize. It was led by Prime Minister Nicolas Tiangaye, a former lawyer and member of the civilian opposition.

Seleka, a loose coalition of five rebel groups whose name means 'alliance' in the Songo language, had accused Bozize of breaking the January agreement by failing to integrate their fighters into the army.

(Reporting by Aaron Maasho; Writing by Edmund Blair; Editing by Andrew Heavens)

Source: http://news.yahoo.com/central-african-republic-suspended-african-union-says-official-131219253.html

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Sunday, 24 March 2013

1 dead, 1 injured after Utah mine collapse

By James Nelson, Reuters

SALT LAKE CITY - A miner was killed and another injured on Friday when part of a tunnel roof collapsed at a coal mine in central Utah, authorities said.

The miner was killed in the cave-in at the Rhino mine in Bear Canyon, 10 miles from Huntington in central Utah, which was reported shortly after 3 p.m. local time, the Emery County Sheriff's Office said.

Rescue workers recovered one injured miner at the site, who was taken to the Castleview Hospital in Price, Utah, for treatment, Sheriff's office spokeswoman Molly Barnes said.

"Members of the Rhino mine rescue team have recovered the body of the second coal miner," Barnes said. She said his identity would not be released until his family had been informed.

The Rhino mine is part of the Castle Valley Mining Complex, according to news reports. A call to Rhino Resource Partners, which owns the operation in Emery and Carbon Counties, Utah, was not returned.

The mine is just a few miles from a coal mine at Crandall Canyon, Utah, where a collapse in August 2007 trapped and killed six workers 1,800 feet underground in a cave-in so powerful that it caused a magnitude 3.9 seismic waves.

Three rescue workers were killed in a second collapse ten days after the initial disaster.

Joe Piccolo, the mayor of the nearby mining town of Price, where the injured miner was taken for treatment, said local communities in the Utah coal belt had "always sustained themselves through grief stricken situations."

"It's a dangerous occupation, but we will pull together," he told Reuters.

Barnes could not confirm the condition of the injured miner. Piccolo said he had been treated and released from hospital.

Related:

Workers rescued from mile-deep Idaho mine

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Use the iUSBportCAMERA and your mobile device or computer to control your DSLR

Earlier this year, we told you about an accessory that allows you to use your iOS device as a trigger/timer/intervalometer for your DSLR camera. ?The iUSBportCAMERA accessory from HyperShop?is a similar product with more features. ?First of all, you can use this device with iOS and Android mobile devices or your Mac or Windows computer. [...]

Source: http://the-gadgeteer.com/2013/03/22/use-the-iusbportcamera-and-your-mobile-device-or-computer-to-control-your-dslr/

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Saturday, 23 March 2013

First migration from Africa less than 95,000 years ago: Ancient hunter-gatherer DNA challenges theory of early out-of-Africa migrations

Mar. 22, 2013 ? Recent measurements of the rate at which children show DNA changes not seen in their parents -- the "mutation rate" -- have challenged views about major dates in human evolution.

In particular these measurements have made geneticists think again about key dates in human evolution, like when modern non-Africans split from modern Africans. The recent measurements push back the best estimates of these dates by up to a factor of two. Now, however an international team led by researchers at the University of T?bingen and the Max Planck Institute for Evolutionary Anthropology in Leipzig, present results that point again to the more recent dates. The new study is published in Current Biology.

The team, led by Johannes Krause from T?bingen University, was able to reconstruct more than ten mitochondrial genomes (mtDNAs) from modern humans from Eurasia that span 40,000 years of prehistory. The samples include some of the oldest modern human fossils from Europe such as the triple burial from Dolni Vestonice in the Czech Republic, as well as the oldest modern human skeletons found in Germany from the site of Oberkassel close to Bonn.

The researchers show that pre-ice age hunter-gatherers from Europe carry mtDNA that is related to that seen in post-ice age modern humans such as the Oberkassel fossils. This suggests that there was population continuity throughout the last major glaciation event in Europe around 20,000 years ago. Two of the Dolni Vestonice hunter-gatherers also carry identical mtDNAs, suggesting a close maternal relationship among these individuals who were buried together.

The researchers also used the radiocarbon age of the fossils to estimate human mutation rates over tens of thousands of year back in time. This was done by calculating the number of mutations in modern groups that are absent in the ancient groups, since they had not yet existed in the ancient population. The mutation rate was estimated by counting the number of mutations accumulated along descendent lineages since the radiocarbon dated fossils.

Using those novel mutation rates -- capitalizing on information from ancient DNA -- the authors cal-culate the last common ancestor for human mitochondrial lineages to around 160,000 years ago. In other words, all present-day humans have as one of their ancestors a single woman who lived around that time.

The authors also estimate the time since the most recent common ancestor of Africans and non-Africans to between 62,000-95,000 years ago, providing a maximum date for the mass migration of modern humans out of Africa. Those results are in agreement with previous mitochondrial dates based on archaeological and anthropological work but are at the extreme low end of the dates sug-gested from de-novo studies that suggest a split of non-Africans from Africans about thirty thousand years earlier.

"The results from modern family studies and our ancient human DNA studies are in conflict" says Krause. "One possibility is that mutations were missed in the modern family studies, which could lead to underestimated mutation rates." The authors argue that nuclear genomes from ancient mod-ern humans may help to explain the discrepancies.

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The above story is reprinted from materials provided by Universitat Tuebingen.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Qiaomei Fu, Alissa Mittnik, Philip?L.F. Johnson, Kirsten Bos, Martina Lari, Ruth Bollongino, Chengkai Sun, Liane Giemsch, Ralf Schmitz, Joachim Burger, Anna?Maria Ronchitelli, Fabio Martini, Renata?G. Cremonesi, Ji?? Svoboda, Peter Bauer, David Caramelli, Sergi Castellano, David Reich, Svante P??bo, Johannes Krause. A Revised Timescale for Human Evolution Based on Ancient Mitochondrial Genomes. Current Biology, 2013; DOI: 10.1016/j.cub.2013.02.044

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_environment/~3/c-Da9OT7Sh0/130322114856.htm

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Obama withdraws nomination of Caitlin Halligan to D.C. Circuit Court of Appeals (Washington Post)

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Friday, 22 March 2013

Read A Rule-Breaking Cover Letter From A Young Eudora Welty

weltyBorn in Jackson, Mississippi in 1909, Eudora Welty was one of the greatest writers the American South produced. In 1933, however, she was just a recent college grad, ?six weeks on the loose in N.Y.,? and she needed a job. In pursuit of that, she wrote one of the most charming cover letters I?ve ever read. That letter to the New Yorker breaks all the rules of cover letters: It?s too long, it meanders far from her accomplishments and qualifications, she makes a cheesy pun, she insults her most recent job, and she speaks openly of needing money. But it?s also beautiful and intriguing, and she promises ?I would work like a slave,? which every employer wants to hear.

An excerpt:

I am 23 years old, six weeks on the loose in N.Y. However, I was a New Yorker for a whole year in 1930-31 while attending advertising classes in Columbia?s School of Business. Actually I am a southerner, from Mississippi, the nation?s most backward state. Ramifications include Walter H. Page, who, unluckily for me, is no longer connected with Doubleday-Page, which is no longer Doubleday-Page, even. I have a B.A. (?29) from the University of Wisconsin, where I majored in English without a care in the world. For the last eighteen months I was languishing in my own office in a radio station in Jackson, Miss., writing continuities, dramas, mule feed advertisements, santa claus talks, and life insurance playlets; now I have given that up.

She didn?t get the job, despite warning in the letter that ?there is no telling where I may apply, if you turn me down.? More?s the pity for the New Yorker, but everything worked out fine for young Ms. Welty in the end. She would go on to win a Pulitzer Prize, the Presidential Medal of Freedom and many, many other awards. Oh, and she also had seven short stories published in the New Yorker.

You can read the full letter at the great Letters of Note.

Photo: Books as Food

Source: http://www.thegrindstone.com/2013/03/22/work-life-balance/eudora-welty-cover-letter-new-yorker/?utm_source=rss&utm_medium=rss&utm_campaign=eudora-welty-cover-letter-new-yorker

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Death toll rises to 20 in Myanmar religious riots

MEIKHTILA, Myanmar (AP) ? Two days of rioting between Buddhists and Muslims in a central Myanmar town has killed at least 20 and left residents too afraid to walk the streets, a lawmaker said Friday.

There was no immediate sign of fresh violence Friday morning but the town of Meikhtila remained tense and dangerous, said Win Htein, a local lawmaker from the opposition National League for Democracy.

Fires set to Muslim homes continued to burn but angry Buddhist residents and monks prevented authorities from putting out the blazes, he said.

At least five mosques were torched during the violence that started Wednesday, reportedly triggered by an argument between a Muslim gold shop owner and his Buddhist customers. A Buddhist monk was among the first killed, inflaming tensions that led a Buddhist mob to rampage through a Muslim neighborhood.

Meikhtila is about 550 kilometers (340 miles) north of the main city of Yangon with a population of about 100,000 people, of which about a third are Muslims, Win Htein said. He said before this week's violence, the community had 17 mosques.

It was difficult to determine the extent of destruction in the town because residents were too afraid to walk the streets and were sheltering in monasteries or other locations away from the violence.

"We don't feel safe and we have now moved inside a monastery," said Sein Shwe, a shop owner. "The situation is unpredictable and dangerous."

Occasional isolated violence involving Myanmar's majority Buddhist and minority Muslim communities has occurred for decades.

The violence in Meikhtila was the latest sectarian unrest after clashes between Rakhine Buddhists and Muslim Rohingya last year in western Rakhine state left more than 200 people dead and 100,000 homeless.

It is also the latest challenge for the government as it tries to keep peace in the country and navigate the transition from military rule to fledgling democracy.

Source: http://news.yahoo.com/death-toll-rises-20-myanmar-religious-riots-051933236.html

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Thursday, 21 March 2013

Hyundai teases with Concept HND-9 renderings

Hyundai's HND-9 high-performance sports coupe concept

Hyundai's HND-9 high-performance sports coupe concept

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Hyundai has released design sketches of its latest concept car ahead of a world premiere at the 2013 Seoul Motor Show later this month. Like the HCD-14 Genesis concept shown in Detroit, the HND-9 concept aims to spell out the company's future design direction for its luxury offerings ? this time with an extra dose of sporty.

The HND-9 is described as "a modern interpretation of a classic premium sports coupe" and apart from the butterfly doors and some interesting curves on all four corners, the renderings suggest the HND-9 leans towards the less radical side of such an interpretation ? which isn't to say it's without appeal.

Technical details are scarce ? rear-wheel drive with a 3.3-litre turbo GDi engine married to an 8-speed auto transmission for a maximum output of 270 kW. That's all we know until Hyundai lifts the lid on the HND-9 in Seoul on March 28.

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Source: http://www.gizmag.com/hyundai-concept-hnd-9-seoul/26748/

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'Brain waves' challenge area-specific view of brain activity

Mar. 20, 2013 ? Our understanding of brain activity has traditionally been linked to brain areas ? when we speak, the speech area of the brain is active. New research by an international team of psychologists led by David Alexander and Cees van Leeuwen (KU Leuven ? University of Leuven) shows that this view may be overly rigid. The entire cortex, not just the area responsible for a certain function, is activated when a given task is initiated. Furthermore, activity occurs in a pattern: waves of activity roll from one side of the brain to the other.

The brain can be studied on various scales, researcher David Alexander explains: "You have the neurons, the circuits between the neurons, the Brodmann areas ? brain areas that correspond to a certain function ? and the entire cortex. Traditionally, scientists looked at local activity when studying brain activity, for example, activity in the Brodmann areas. To do this, you take EEG's (electroencephalograms) to measure the brain?s electrical activity while a subject performs a task and then you try to trace that activity back to one or more brain areas."

In this study, the psychologists explore uncharted territory: "We are examining the activity in the cerebral cortex as a whole.?The brain is a non-stop, always-active system.?When we perceive something, the information does not end up in a specific part of our brain. Rather, it is added to the brain's existing activity. If we measure the electrochemical activity of the whole cortex, we find wave-like patterns. This shows that brain activity is not local but rather that activity constantly moves from one part of the brain to another. The local activity in the Brodmann areas only appears when you average over many such waves.?

Each activity wave in the cerebral cortex is unique. "When someone repeats the same action, such as drumming their fingers, the motor centre in the brain is stimulated. But with each individual action, you still get a different wave across the cortex as a whole. Perhaps the person was more engaged in the action the first time than he was the second time, or perhaps he had something else on his mind or had a different intention for the action. The direction of the waves is also meaningful. It is already clear, for example, that activity waves related to orienting move differently in children ? more prominently from back to front ? than in adults. With further research, we hope to unravel what these different wave trajectories mean."

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The above story is reprinted from materials provided by KU Leuven.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. David M. Alexander, Peter Jurica, Chris Trengove, Andrey R. Nikolaev, Sergei Gepshtein, Mikhail Zvyagintsev, Klaus Mathiak, Andreas Schulze-Bonhage, Johanna Ruescher, Tonio Ball, Cees van Leeuwen. Traveling waves and trial averaging: The nature of single-trial and averaged brain responses in large-scale cortical signals. NeuroImage, 2013; 73: 95 DOI: 10.1016/j.neuroimage.2013.01.016

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/H4AziyFrJDQ/130320115111.htm

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How do House and Senate budget proposals compare?

How the budget proposals by Senate Democrats and House Republicans stack up over the next decade:

___

Total spending

Senate Democrats: $46.5 trillion.

House Republicans: $41.7 trillion.

___

Total Revenue

Senate Democrats: $41.2 trillion.

House Republicans: $40.2 trillion.

___

10-year Deficit

Senate Democrats: $5.4 trillion.

House Republicans: $1.4 trillion.

___

National debt at end of 2023

Senate Democrats: $24.4 trillion.

House Republicans: $20.3 trillion.

___

Social Security

Senate Democrats: $11.3 trillion.

House Republicans: $11.3 trillion.

___

Medicare

Senate Democrats: $6.8 trillion.

House Republicans: $6.7 trillion.

___

Health, including Medicaid and the State Children's Health Insurance Program. The House Republican plan eliminates funding for President Barack Obama's health care law and turns Medicaid into a block grant for states.

Senate Democrats: $6.6 trillion.

House Republicans: $4.0 trillion.

___

National Defense

Senate Democrats: $6.0 trillion.

House Republicans: $6.2 trillion.

___

Income security, including housing assistance, cash benefits and food stamps

Senate Democrats: $5.6 trillion.

House Republicans: $5.0 trillion.

___

Interest on national debt

Senate Democrats: $5.2 trillion.

House Republicans: $4.5 trillion.

___

Veterans benefits and services

Senate Democrats: $1.7 trillion.

House Republicans: $1.7 trillion.

___

International Affairs, including foreign aid

Senate Democrats: $506 billion.

House Republicans: $431 billion.

___

Education, training, employment and social services

Senate Democrats: $1.1 trillion.

House Republicans: $906 billion.

___

Transportation

Senate Democrats: $919 billion.

House Republicans: $801 billion.

___

Agriculture

Senate Democrats: $205 billion.

House Republicans: $196 billion.

___

Natural resources and environment.

Senate Democrats: $474 billion.

House Republicans: $385 billion.

___

Community and regional development

Senate Democrats: $268 billion.

House Republicans: $88 billion.

___

Sources: Senate Democratic and House Republican budget proposals.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2013-03-19-US-Budget-Battle-Plan-Highlights/id-e10584dbd4724129b8024261ccefcede

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Wednesday, 20 March 2013

International finance: The end of an era? | The Economist

PAUL KRUGMAN writes:

Let me make a broader point: we?ve now seen three island nations around Europe become huge international banking hubs relative to their GDPs, then get into crisis because their domestic economies don?t have the resources to bail out those metastasized banking systems if something goes wrong. This strongly suggests, to me at least, that we have a fundamental problem with the whole architecture (to use the preferred fancy word) of international finance...

All of which raises the question, is the era of free capital movement just a bubble, fated to end one of these years, maybe soon?

Hm. Well, the world's second largest economy maintains very tight controls over capital flows. The third largest economy is actively engaged in managing its currency. The sixth-largest economy has used capital controls to limit appreciation of its currency. Many of the world's other large economies are part of a monetary union actively experimenting with a handful of financial-repression mechanisms. The International Monetary Fund has taken the official position that the use of capital controls may be warranted as a financial stability tool. And so on. I would say that the era of free capital mobility is definitely on life-support.

Now, many of these policies may be designed to be temporary. And China looks interested in gradual liberalisation of its capital controls. But there are two reasons to think that the trend will continue toward less rather than more mobility. One is that a half-open world is probably not a stable equilibrium. Everyone can hold hands and jump into mobility and create a stable equilibrium that way. But as some defect from that equilibrium openness begins to look much less attractive for the others, who may absorb outsize inflows or outflows, or who may bear the brunt of others' currency manipulation. One might argue that open countries will therefore press others to return to the open equilibrium, but that moves us to the second issue: capital flow restrictions will be very useful to countries interested in using a bit of inflation to chip away at high debt levels. And that includes just about everyone.

Source: http://www.economist.com/blogs/freeexchange/2013/03/international-finance

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CA-NEWS Summary

Cyprus lawmakers reject bank tax; bailout in disarray

NICOSIA (Reuters) - Cyprus overwhelmingly rejected a proposed levy on bank deposits as a condition for a European bailout on Tuesday, throwing international efforts to rescue the latest casualty of the euro zone debt crisis into disarray. The vote in the tiny legislature was a stunning setback for the 17-nation currency bloc, angering European partners and raising fears the crisis could spread; lawmakers in Greece, Portugal, Ireland, Spain and Italy have all accepted austerity measures over the last three years to secure European aid.

Obama heads to Israel amid low expectations

JERUSALEM (Reuters) - President Barack Obama arrives in Israel on Wednesday without any new peace initiative to offer disillusioned Palestinians and facing deep Israeli doubts over his pledge to prevent a nuclear-armed Iran. Making his first official visit here as president, Obama hopes to reset his often fraught relations with both the Israelis and Palestinians in a carefully choreographed three-day stay that is high on symbolism but low on expectations.

Al Qaeda in Africa says it beheads French hostage: agency

NOUAKCHOTT (Reuters) - Al Qaeda's wing in north Africa said it had beheaded a French hostage in retaliation for France's intervention in Mali, Mauritania's ANI news agency reported on Tuesday, citing a spokesman for the group. In what ANI reported was a telephone call to the agency, which has close links to Islamist militants, the commander said Philippe Verdon had been beheaded on March 10 "in response to the French military intervention in the north of Mali", ANI reported.

China's new diplomats signal thaw with Japan, keeping U.S. at bay

BEIJING (Reuters) - New Chinese leader Xi Jinping's appointment of two top diplomats last week displays a desire to repair relations with long-time rival Japan after months of disruption, while keeping the United States and its strategic pivot to Asia at bay. Yang Jiechi, a hard-nosed former ambassador to Washington, has been named the state councilor in charge of the foreign ministry, its top post. A fluent English-speaker, he firmly believes the United States should stay out of regional Asian affairs such as the South China Sea dispute.

Pope sets tone for humbler papacy, calls for defense of the weak

VATICAN CITY (Reuters) - Pope Francis set the tone for a new, humbler papacy at his inaugural Mass on Tuesday where he called for the Church to defend the weak and protect the environment. Addressing up to 200,000 people including many foreign leaders gathered under bright sunshine in St. Peter's Square, the Argentine pope underlined his central message since he was elected by a secret conclave of cardinals last Wednesday - that the Church's mission was to defend the poor and disadvantaged.

Alleged chemical attack kills 25 in northern Syria

BEIRUT (Reuters) - Syria's government and rebels accused each other of launching a deadly chemical attack near the northern city of Aleppo on Tuesday in what would, if confirmed, be the first use of such weapons in the two-year conflict. U.S. President Barack Obama, who has resisted overt military intervention in Syria, has warned President Bashar al-Assad that any use of chemical weapons would be a "red line". There has, however, been no suggestion of rebels possessing such arms.

Bombs kill nearly 60 on Iraq invasion anniversary

BAGHDAD (Reuters) - More than a dozen car bombs and suicide blasts tore through Shi'ite Muslim districts in the Iraqi capital Baghdad and other areas on Tuesday, killing nearly 60 people on the 10th anniversary of the U.S.-led invasion that ousted Saddam Hussein. Sunni Islamist insurgents linked to al Qaeda are regaining ground in Iraq, invigorated by the war next door in Syria and have stepped up attacks on Shi'ite targets in an attempt to provoke a wider sectarian confrontation.

U.S. working out transfer of Congo war suspect to ICC

KIGALI (Reuters) - The U.S. Embassy in Rwanda was on Tuesday working out the logistics of transferring a Congolese warlord to the International Criminal Court (ICC), a day after Bosco Ntaganda walked off the street to face war crimes charges. Ntaganda stunned embassy staff in Kigali when he gave himself up, a seemingly meek end to a 15-year long career that saw him fight as a rebel and government soldier on both sides of the Rwanda-Congo border.

U.N. arms embargoes don't work, arms treaty needed: rights group

UNITED NATIONS (Reuters) - U.N. arms embargoes inevitably fail because international arms trade is a virtual free-for-all due to the lack of regulation for the $70 billion global weapons commerce, the rights group Amnesty International said on Tuesday. "The United Nations Security Council arms embargoes are always flouted and circumvented and violated because the system of state regulation around the world is not strict enough," Brian Wood, Amnesty's head of arms control and human rights said on the sidelines of a U.N. arms treaty drafting conference.

Rwanda refuses visas for two U.N. Congo sanctions experts

UNITED NATIONS (Reuters) - Rwanda has refused to issue entry visas to two members of a U.N. expert panel that accused Kigali last year of arming rebels in eastern Democratic Republic of the Congo, describing them as biased, Rwandan and other diplomats said on Tuesday. Several U.N. diplomats, speaking on condition of anonymity, disputed the allegations of bias.

Source: http://news.yahoo.com/ca-news-summary-000945250.html

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